Label-free and labeled technologies together. See the benchtop in a whole new way.

Call it the "aha moment," when the complete picture is before you – and suddenly your research has accelerated well beyond where you'd imagined it heading. These moments are what the EnSpire® Multimode Plate Reader was made for.

EnSpire is the only multimode bench-top reader that delivers proven Corning® Epic® label-free technology at higher throughput, alongside labeled platforms. This unique combination provides richer information about cell and biochemical systems, more pathway-independent analysis and more physiologically relevant data – even from difficult or weak targets.

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What are the benefits of label-free assays?

  • Complements labeled assays with data about the entire pathway for a more complete picture
  • Rich information about cellular and biochemical assays
  • Pathway unbiased analysis of endogenously and recombinantly expressed targets
  • Non-invasive, more physiologically relevant data
  • Study difficult targets (e.g. GPCRs) or weak biological interactions

Choose from a range of labeled technologies including:

  • Alpha® Technology
  • Luminescence
  • Fluorescence
  • Time-resolved Fluorescence

Visit the website to learn more:

Download the Application Note on
Pathway Independent Cell-based Assays
Download the Application Note on Receptor Activation in Primary and Mesenchymal Stem Cells



Peer reviewed publications
Applying label-free dynamic mass redistribution technology to frame signalling of G protein-coupled receptors non-invasively in living cells. R. Schröder et al., Nature Protocols, 2011, 6, 1748-1760.

GPR35 is a target of the loop diuretic drugs bumetanide and furosemide. Y. Yang, Pharmacology, 2012, 89, 13-17.